Global health review
A weekly round-up of all the latest global health research from MSF projects and beyond
4 September 2026
Looking ahead to 2027, abstract submissions are now open for MSF Paediatric Days, taking place in Dakar, Senegal, on 15–16 April. The event brings together MSF colleagues and partners to share research, experiences and lessons from paediatric care across humanitarian settings. Abstracts can be submitted until 4 October 2026, so head to the MSF Paediatric Days website to make your submission.
This week, in The Lancet Child and Adolescent Health, MSF authors call for the urgent inclusion of children and people who are pregnant or breastfeeding in research on post-exposure prophylaxis for Bundibugyo virus, arguing that their continued exclusion from trials denies those at highest risk access to potentially lifesaving treatments. Similarly, in PLOS Global Public Health, an opinion piece with MSF contribution calls for earlier access to vaccines and treatments for children during the current Ebola outbreak, warning that delays in developing paediatric options can cost lives.
A DNDi article published in PLOS Neglected Tropical Diseases reports a new analysis of data from the first-in-human study of DNDI-6148, a potential new treatment for leishmaniasis and Chagas disease. The analysis provides new evidence on how the drug behaves in the body at different doses, helping to inform appropriate dose selection for future clinical trials.
Finally, in PLOS Medicine, a new study on the global burden of snakebite estimates at least 2.1 million cases of envenoming and 274,000 deaths each year. The findings suggest the scale of the problem may have been substantially underestimated in the past, with low-income countries bearing the greatest burden and sub-Saharan Africa accounting for nearly half of cases and deaths globally.
Best regards,
Clara Von Kaehne, Rosie Wharton, Lillian Matthes, and Holly Baker with MSF-authored article assistance from Alys Barton and Amelia Zhao.
All MSF-authored publications can be found on the MSF Science Portal, as well as recordings, abstracts and posters from the MSF Scientific Days 2026 conference.
Antimicrobial resistance
PLOS Medicine • Perspectives: Antimicrobial stewardship in low- and middle-income countries: Access versus adherence
BMC Health Services Research • Article: Healthcare providers’ perspectives regarding unregulated antibiotic use in Southern Pakistan: a qualitative study
BMC Health Services Research • Article: Audit of nosocomial infection control’s committee operation and internal policy on hospital hygiene and use of antibiotics in Benin: similarities and gaps between norms and practices
Conflict, migration and health
The Lancet Regional Health Europe • Article: War-related displacement, conflict intensity, and treatment delivery factors in opioid agonist maintenance treatment discontinuation following Russia's invasion of Ukraine: a national cohort study
The Lancet Regional Health Europe • Article: Effectiveness of the hope groups intervention on mental health, parenting practices, and violence against children among Ukrainian parents and caregivers affected by war and displacement: a cluster randomised controlled trial
The BMJ • News***MENTIONS MSF***: Gaza: Israel refuses to open criminal investigation into MSF staff killed by military
The BMJ • Feature***MENTIONS MSF***: Rohingya refugees remain trapped in a deadly limbo nine years after fleeing persecution
The BMJ • Editorial: Afghanistan to Gaza: Protecting women’s health through conflict and instability
BMJ Global Health • Article: Impact of Russian invasion on radiation therapy capacity in Ukraine: a national survey study
Conflict and Health • Review: Trust in the conduct of health and implementation research in conflict-induced humanitarian settings: a narrative literature review and preliminary theoretical framework
Conflict and Health • Article: Household hunger and depression, anxiety, and stress symptoms among online survey respondents in gaza during the 2023–2025 war: a cross-sectional study
Conflict and Health • Article: Disclosure and help-seeking experiences of childhood sexual violence survivors in refugee settings of Ethiopia and Uganda
BMC Health Services Research • Article: Perceived difficulty accessing primary health care in a violence-affected community in the municipality of Rio de Janeiro, by sociodemographic characteristics and mental health status, 2024
Ebola
The Lancet Infectious Diseases • Article: Evaluating the impact of antiviral post-exposure prophylaxis for health-care workers during orthoebolavirus outbreaks: a modelling study
The Lancet Global Health • Comment: Operational bottlenecks in the response to Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: a call to action
The BMJ • News: Ebola: WHO declares Uganda free of virus, but doctors express reservations about new vaccine trial
PLOS Global Public Health • Article: Operational epidemiology of the early phase of the 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo and Uganda
Global health
BMJ Global Health • Article: Performance in reducing child stunting in Africa: a stochastic frontier analysis of 54 countries over the past two decades (2000–2022)
PLOS Medicine • Article: Estimates of global burden of snakebite: A literature review and geostatistical modelling study
HIV
The Lancet HIV • Review: Epidemiology and management of HIV-2
The Lancet Regional Health Americas • Article: PrEP reinitiation, uptake, and persistence as targets for reducing HIV incidence and racial and ethnic inequities among men who have sex with men in Boston, USA: a network modeling study
BMC Health Services Research • Article: Divergent perceptions of HIV stigma in healthcare facilities: a multi-stakeholder study in Denpasar, Indonesia
PLOS Global Public Health • Article: Mental health and psychosocial support among refugee children and adolescents with HIV in West Nile Uganda: An exploratory study
Infectious diseases
The Lancet • Article: Infection-triggered encephalopathy syndromes: a meta-analysis of clinical characteristics and outcomes in 1946 cases
The Lancet Microbe • Article: Profiling the dynamics of maternally acquired and infection-induced antibodies against influenza B in early childhood: a longitudinal paired mother–infant cohort study from southern China
The BMJ • News: Giardia: UK cases of diarrhoea causing parasite reach 10 year high
The BMJ • News: Measles: Australia at risk of losing herd immunity, study suggests
Clinical Infectious Diseases • Comment: Difficult Diagnosis: C. Difficile Without Diarrhea
Clinical Infectious Diseases • Article: A New Paradigm for Clostridioides difficile Infection: Atypical Presentations Correlating to Acute Gastrointestinal Dysmotility Are Associated With Increased Mortality
Malaria
The Lancet Regional Health Southeast Asia • Article: Seven-day versus fourteen-day low-dose primaquine for Plasmodium vivax malaria in India: an open-label, non-inferiority, randomised, controlled trial
The Lancet Regional Health Western Pacific • Article: Validation of serological markers of recent exposure to Plasmodium vivax in Cambodia: a longitudinal cohort and cross-sectional study
Transactions of The Royal Society of Tropical Medicine and Hygiene • Article: Establishment of Anopheles stephensi in a former Anopheles arabiensis Sterile Insect Technique project area in northern Sudan
Malaria Journal • Article: Patterns and factors associated with mothers’ willingness to vaccinate their children against malaria in Uganda: evidence from a nationally representative survey
Malaria Journal • Article: Improving malaria microscopy performance through structured refresher training: evidence from India for diagnosis of malaria
Malaria Journal • Perspectives: Advancing complement inhibition for the treatment of malarial anemia: a translational roadmap
Maternal and child health
PLOS Medicine • Article: Trends of stillbirth, early neonatal and perinatal mortality rates and sociodemographic differentials of perinatal mortality rates in 17 low- and middle-income countries: A modeling study
PLOS Global Public Health • Article: Women’s knowledge, attitudes and practices related to mother-to-child transmission of HTLV-1 in Peru
Mental health
The BMJ • News: Psychiatrist leaders apologise for failures of care for survivors of childhood sexual abuse
Conflict and Health • Article: Barriers and facilitators to integrating mental health and psychosocial support into economic inclusion programming for displaced families in ecuador
Neglected tropical diseases
The Lancet Global Health • Article: Prevalence, characteristics, and clinical course of mpox-related ophthalmic disease (MBOTE-EYE): a prospective cohort study in South Kivu, Democratic Republic of the Congo
The Lancet Microbe • Article: Genomic analysis of Echinococcus granulosus sensu stricto: genetic diversity and population structure
BMJ Global Health • Practice: Overcoming the last mile: practical strategies for leprosy elimination in Pakistan
PLOS Neglected Tropical Diseases • Viewpoint: Trypanosoma cruzi infection in pregnancy: New approaches to address the diagnosis and follow-up of women and newborns
PLOS Neglected Tropical Diseases • Article: Prevalence and associated risk factors of self-reported symptoms suggestive of female genital schistosomiasis (FGS) among women in KwaZulu-Natal, South Africa
PLOS Neglected Tropical Diseases • Article: Impact and cost-effectiveness of water, sanitation, hygiene, and health education interventions in the control and elimination of soil-transmitted helminthiasis: A scoping review
PLOS Neglected Tropical Diseases • Article: Climate-driven spatiotemporal dynamics of Aedes infestation and dengue transmission in Porto Alegre, Southern Brazil
Transactions of The Royal Society of Tropical Medicine and Hygiene • Review: Neglected arboviruses in South America: clinical manifestations and diagnostic challenges
Transactions of The Royal Society of Tropical Medicine and Hygiene • Article: Fistula formation in hepatic cystic echinococcosis: clinical impact, predictors, and outcomes from a 27-year cohort
BMC Health Services Research • Article: Examining knowledge of Mpox among primary care physicians in North-Western Nigeria: an online cross-sectional study
PLOS Global Public Health • Article: Delayed diagnosis as a barrier to Zero Leprosy: Lived experiences from Pakistan
Non-communicable diseases
The Lancet Regional Health Africa • Article: Prevalence and risk factors of CKD in sub-Saharan Africa, 2015–2024: a systematic review and critical appraisal of knowledge gaps
The BMJ • Article: Intravenous iron to treat anaemia before cardiac surgery (ITACS): international, double blind, placebo controlled randomised trial
The New England Journal of Medicine • Article: Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis
Clinical Infectious Diseases • Article: Should valve leaflet thickening be considered a characteristic lesion of infective endocarditis?
Clinical Infectious Diseases • Comment: Nuanced Diagnosis of Infective Endocarditis: When Isolated Valve Leaflet Thickening on Cardiac Imaging is Inadequate for Diagnosis of Infective Endocarditis
Outbreaks
The BMJ • News: UK salmonella outbreak: Cases rise as another death is recorded
The BMJ • News: “Rain rot”: first case of this sexually transmitted skin infection is detected in UK
PLOS Neglected Tropical Diseases • Article: Clinical and epidemiological characteristics of the 2025 dengue outbreak in Bangladesh
PLOS Neglected Tropical Diseases • Article: Acute-phase clinical profile and quality of life in patients with chikungunya during the 2025 outbreak in Bangladesh: A facility-based cross-sectional study
JAMA Network • News: Measles in the Americas 3 Times Higher Than in All of 2025, PAHO Warns
Transactions of The Royal Society of Tropical Medicine and Hygiene • Comment: A pandemic stops being an emergency? After 65 years, that question has become increasingly relevant for cholera
Research and reporting
The Lancet Regional Health Africa • Article: Strengthening alcohol control policies in Kenya: an analysis of policy comprehensiveness and restrictiveness
The Lancet Regional Health Americas • Article: Environmental and public health outcomes following the Fundão dam collapse (Mariana, Brazil): a retrospective ecological study of drinking water quality and cancer mortality
Sexual and reproductive health
BMJ Global Health • Article: Preferences for characteristics of contraceptive methods: a large, multi-country discrete choice experiment
BMJ Global Health • Article: Scaling pleasure-based sexual and reproductive health: an impact and economic modelling study in 99 low- and middle-income countries
BMC Health Services Research • Article: From centralised policy development to uneven implementation: a qualitative study of adolescent reproductive health policy processes at the national level and in Southwestern Uganda
Tuberculosis
The New England Journal of Medicine • Case Study: Scrofuloderma
Vaccines
The Lancet Regional Health Europe • Article: The effect of HPV vaccination on precancerous lesions and invasive cervical cancer in a low-vaccination-coverage setting in Germany: a retrospective cohort analysis
The Lancet Infectious Diseases • Article: Safety and immunogenicity of GBS6 in pregnant women living with and without HIV and their infants in Uganda (PREPARE WP4): a double-blind, randomised, placebo-controlled, phase 2 clinical trial
The Lancet Infectious Diseases • and comment: Curbing neonatal group B streptococcus disease burden
The BMJ • News: Shingles vaccine is linked to lower risk of heart disease and stroke, study suggests
The BMJ • News: What are the real risks of covid vaccines and miscarriage?
Conflict and Health • Review***MENTIONS MSF***: Barriers & coverage outcomes of inactivated polio vaccine & oral polio vaccine in humanitarian settings: a scoping review
BMC Health Services Research • Review: Awareness, knowledge, acceptance, and uptake of hepatitis B vaccines among healthcare workers in Nigeria: a scoping review