Global health review

MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh. Caption
MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh.

A weekly round-up of all the latest global health research from MSF projects and beyond

4 September 2026

Looking ahead to 2027, abstract submissions are now open for MSF Paediatric Days, taking place in Dakar, Senegal, on 15–16 April. The event brings together MSF colleagues and partners to share research, experiences and lessons from paediatric care across humanitarian settings. Abstracts can be submitted until 4 October 2026, so head to the MSF Paediatric Days website to make your submission.  

 

This week, in The Lancet Child and Adolescent Health, MSF authors call for the urgent inclusion of children and people who are pregnant or breastfeeding in research on post-exposure prophylaxis for Bundibugyo virus, arguing that their continued exclusion from trials denies those at highest risk access to potentially lifesaving treatments. Similarly, in PLOS Global Public Health, an opinion piece with MSF contribution calls for earlier access to vaccines and treatments for children during the current Ebola outbreak, warning that delays in developing paediatric options can cost lives.  

 

A DNDi article published in PLOS Neglected Tropical Diseases reports a new analysis of data from the first-in-human study of DNDI-6148, a potential new treatment for leishmaniasis and Chagas disease. The analysis provides new evidence on how the drug behaves in the body at different doses, helping to inform appropriate dose selection for future clinical trials.

 

Finally, in PLOS Medicine, a new study on the global burden of snakebite estimates at least 2.1 million cases of envenoming and 274,000 deaths each year. The findings suggest the scale of the problem may have been substantially underestimated in the past, with low-income countries bearing the greatest burden and sub-Saharan Africa accounting for nearly half of cases and deaths globally.

 

Best regards,

 

Clara Von Kaehne, Rosie Wharton, Lillian Matthes, and Holly Baker with MSF-authored article assistance from Alys Barton and Amelia Zhao.

 

All MSF-authored publications can be found on the MSF Science Portal, as well as recordings, abstracts and posters from the MSF Scientific Days 2026 conference.

Antimicrobial resistance

PLOS Medicine • Perspectives: Antimicrobial stewardship in low- and middle-income countries: Access versus adherence

BMC Health Services Research • Article: Healthcare providers’ perspectives regarding unregulated antibiotic use in Southern Pakistan: a qualitative study

BMC Health Services Research • Article: Audit of nosocomial infection control’s committee operation and internal policy on hospital hygiene and use of antibiotics in Benin: similarities and gaps between norms and practices

 

Conflict, migration and health

The Lancet Regional Health Europe • Article: War-related displacement, conflict intensity, and treatment delivery factors in opioid agonist maintenance treatment discontinuation following Russia's invasion of Ukraine: a national cohort study

The Lancet Regional Health Europe • Article: Effectiveness of the hope groups intervention on mental health, parenting practices, and violence against children among Ukrainian parents and caregivers affected by war and displacement: a cluster randomised controlled trial

The BMJ • News***MENTIONS MSF***: Gaza: Israel refuses to open criminal investigation into MSF staff killed by military

The BMJ • Feature***MENTIONS MSF***: Rohingya refugees remain trapped in a deadly limbo nine years after fleeing persecution

The BMJ • Editorial: Afghanistan to Gaza: Protecting women’s health through conflict and instability

BMJ Global Health • Article: Impact of Russian invasion on radiation therapy capacity in Ukraine: a national survey study

Conflict and Health • Review: Trust in the conduct of health and implementation research in conflict-induced humanitarian settings: a narrative literature review and preliminary theoretical framework

Conflict and Health • Article: Household hunger and depression, anxiety, and stress symptoms among online survey respondents in gaza during the 2023–2025 war: a cross-sectional study

Conflict and Health • Article: Disclosure and help-seeking experiences of childhood sexual violence survivors in refugee settings of Ethiopia and Uganda

BMC Health Services Research • Article: Perceived difficulty accessing primary health care in a violence-affected community in the municipality of Rio de Janeiro, by sociodemographic characteristics and mental health status, 2024

 

Ebola

The Lancet • Article: Bundibugyo virus glycoprotein seroreactivity following recombinant vesicular stomatitis virus–Zaire Ebola virus glycoprotein vaccination in outbreak-affected populations of the Democratic Republic of the Congo: a longitudinal cohort study

The Lancet Infectious Diseases • Article: Evaluating the impact of antiviral post-exposure prophylaxis for health-care workers during orthoebolavirus outbreaks: a modelling study

The Lancet Global Health • Comment: Operational bottlenecks in the response to Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: a call to action

The BMJ • News: Ebola: WHO declares Uganda free of virus, but doctors express reservations about new vaccine trial

PLOS Global Public Health • Article: Operational epidemiology of the early phase of the 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo and Uganda
 

Global health

BMJ Global Health • Article: Performance in reducing child stunting in Africa: a stochastic frontier analysis of 54 countries over the past two decades (2000–2022)

PLOS Medicine • Article: Estimates of global burden of snakebite: A literature review and geostatistical modelling study

 

HIV

The Lancet HIV • Review: Epidemiology and management of HIV-2

The Lancet Regional Health Americas • Article: PrEP reinitiation, uptake, and persistence as targets for reducing HIV incidence and racial and ethnic inequities among men who have sex with men in Boston, USA: a network modeling study

BMC Health Services Research • Article: Divergent perceptions of HIV stigma in healthcare facilities: a multi-stakeholder study in Denpasar, Indonesia

PLOS Global Public Health • Article: Mental health and psychosocial support among refugee children and adolescents with HIV in West Nile Uganda: An exploratory study

 

Infectious diseases

The Lancet • Article: Infection-triggered encephalopathy syndromes: a meta-analysis of clinical characteristics and outcomes in 1946 cases

The Lancet Microbe • Article: Profiling the dynamics of maternally acquired and infection-induced antibodies against influenza B in early childhood: a longitudinal paired mother–infant cohort study from southern China

The BMJ • News: Giardia: UK cases of diarrhoea causing parasite reach 10 year high

The BMJ • News: Measles: Australia at risk of losing herd immunity, study suggests

Clinical Infectious Diseases • Comment: Difficult Diagnosis: C. Difficile Without Diarrhea

Clinical Infectious Diseases • Article: A New Paradigm for Clostridioides difficile Infection: Atypical Presentations Correlating to Acute Gastrointestinal Dysmotility Are Associated With Increased Mortality

 

Malaria

The Lancet Regional Health Southeast Asia • Article: Seven-day versus fourteen-day low-dose primaquine for Plasmodium vivax malaria in India: an open-label, non-inferiority, randomised, controlled trial

The Lancet Regional Health Western Pacific • Article: Validation of serological markers of recent exposure to Plasmodium vivax in Cambodia: a longitudinal cohort and cross-sectional study

Transactions of The Royal Society of Tropical Medicine and Hygiene • Article: Establishment of Anopheles stephensi in a former Anopheles arabiensis Sterile Insect Technique project area in northern Sudan

Malaria Journal • Article: Patterns and factors associated with mothers’ willingness to vaccinate their children against malaria in Uganda: evidence from a nationally representative survey

Malaria Journal • Article: Improving malaria microscopy performance through structured refresher training: evidence from India for diagnosis of malaria

Malaria Journal • Perspectives: Advancing complement inhibition for the treatment of malarial anemia: a translational roadmap

 

Maternal and child health

PLOS Medicine • Article: Trends of stillbirth, early neonatal and perinatal mortality rates and sociodemographic differentials of perinatal mortality rates in 17 low- and middle-income countries: A modeling study

PLOS Global Public Health • Article: Women’s knowledge, attitudes and practices related to mother-to-child transmission of HTLV-1 in Peru

 

Mental health

The BMJ • News: Psychiatrist leaders apologise for failures of care for survivors of childhood sexual abuse

Conflict and Health • Article: Barriers and facilitators to integrating mental health and psychosocial support into economic inclusion programming for displaced families in ecuador
 

Neglected tropical diseases

The Lancet Global Health • Article: Prevalence, characteristics, and clinical course of mpox-related ophthalmic disease (MBOTE-EYE): a prospective cohort study in South Kivu, Democratic Republic of the Congo

The Lancet Microbe • Article: Genomic analysis of Echinococcus granulosus sensu stricto: genetic diversity and population structure

BMJ Global Health • Practice: Overcoming the last mile: practical strategies for leprosy elimination in Pakistan

PLOS Neglected Tropical Diseases • Viewpoint: Trypanosoma cruzi infection in pregnancy: New approaches to address the diagnosis and follow-up of women and newborns

PLOS Neglected Tropical Diseases • Article: Prevalence and associated risk factors of self-reported symptoms suggestive of female genital schistosomiasis (FGS) among women in KwaZulu-Natal, South Africa

PLOS Neglected Tropical Diseases • Article: Impact and cost-effectiveness of water, sanitation, hygiene, and health education interventions in the control and elimination of soil-transmitted helminthiasis: A scoping review

PLOS Neglected Tropical Diseases • Article: Climate-driven spatiotemporal dynamics of Aedes infestation and dengue transmission in Porto Alegre, Southern Brazil

Transactions of The Royal Society of Tropical Medicine and Hygiene • Review: Neglected arboviruses in South America: clinical manifestations and diagnostic challenges

Transactions of The Royal Society of Tropical Medicine and Hygiene • Article: Fistula formation in hepatic cystic echinococcosis: clinical impact, predictors, and outcomes from a 27-year cohort

BMC Health Services Research • Article: Examining knowledge of Mpox among primary care physicians in North-Western Nigeria: an online cross-sectional study

PLOS Global Public Health • Article: Delayed diagnosis as a barrier to Zero Leprosy: Lived experiences from Pakistan
 

Non-communicable diseases

The Lancet Regional Health Africa • Article: Prevalence and risk factors of CKD in sub-Saharan Africa, 2015–2024: a systematic review and critical appraisal of knowledge gaps

The BMJ • Article: Intravenous iron to treat anaemia before cardiac surgery (ITACS): international, double blind, placebo controlled randomised trial

The New England Journal of Medicine • Article: Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis

Clinical Infectious Diseases • Article: Should valve leaflet thickening be considered a characteristic lesion of infective endocarditis?

Clinical Infectious Diseases • Comment: Nuanced Diagnosis of Infective Endocarditis: When Isolated Valve Leaflet Thickening on Cardiac Imaging is Inadequate for Diagnosis of Infective Endocarditis

 

Outbreaks

The BMJ • News: UK salmonella outbreak: Cases rise as another death is recorded

The BMJ • News: “Rain rot”: first case of this sexually transmitted skin infection is detected in UK

PLOS Neglected Tropical Diseases • Article: Clinical and epidemiological characteristics of the 2025 dengue outbreak in Bangladesh

PLOS Neglected Tropical Diseases • Article: Acute-phase clinical profile and quality of life in patients with chikungunya during the 2025 outbreak in Bangladesh: A facility-based cross-sectional study

JAMA Network • News: Measles in the Americas 3 Times Higher Than in All of 2025, PAHO Warns

Transactions of The Royal Society of Tropical Medicine and Hygiene • Comment: A pandemic stops being an emergency? After 65 years, that question has become increasingly relevant for cholera
 

Research and reporting

The Lancet Regional Health Africa • Article: Strengthening alcohol control policies in Kenya: an analysis of policy comprehensiveness and restrictiveness

The Lancet Regional Health Americas • Article: Environmental and public health outcomes following the Fundão dam collapse (Mariana, Brazil): a retrospective ecological study of drinking water quality and cancer mortality

 

Sexual and reproductive health

BMJ Global Health • Article: Preferences for characteristics of contraceptive methods: a large, multi-country discrete choice experiment

BMJ Global Health • Article: Scaling pleasure-based sexual and reproductive health: an impact and economic modelling study in 99 low- and middle-income countries

BMC Health Services Research • Article: From centralised policy development to uneven implementation: a qualitative study of adolescent reproductive health policy processes at the national level and in Southwestern Uganda

 

Tuberculosis

The New England Journal of Medicine • Case Study: Scrofuloderma
 

Vaccines

The Lancet Regional Health Europe • Article: The effect of HPV vaccination on precancerous lesions and invasive cervical cancer in a low-vaccination-coverage setting in Germany: a retrospective cohort analysis

The Lancet Infectious Diseases • Article: Safety and immunogenicity of GBS6 in pregnant women living with and without HIV and their infants in Uganda (PREPARE WP4): a double-blind, randomised, placebo-controlled, phase 2 clinical trial

The Lancet Infectious Diseases • and comment: Curbing neonatal group B streptococcus disease burden

The BMJ • News: Shingles vaccine is linked to lower risk of heart disease and stroke, study suggests

The BMJ • News: What are the real risks of covid vaccines and miscarriage?

Conflict and Health • Review***MENTIONS MSF***: Barriers & coverage outcomes of inactivated polio vaccine & oral polio vaccine in humanitarian settings: a scoping review

BMC Health Services Research • Review: Awareness, knowledge, acceptance, and uptake of hepatitis B vaccines among healthcare workers in Nigeria: a scoping review