Global health review

MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh. Caption
MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh.

A weekly round-up of all the latest global health research from MSF projects and beyond

25 September 2026

MSF Scientific Days is back for 2027, taking place in London and online on Thursday 29 April! Save the date, and register your interest to stay up to date with the latest MSF Scientific Days news and event details.

 

As we look ahead to next year, revisit MSF Scientific Days 2026 in the latest PLOS Speaking of Medicine and Health blog post, reflecting on key themes and research findings from this year’s event.

 

This week, in the American Journal of Tropical Medicine and Hygiene, MSF co-authored an article evaluating noninvasive tests for diagnosing visceral leishmaniasis in people living with HIV in Ethiopia. Researchers found that combining urine and blood tests could reduce the need for invasive diagnostic procedures, offering a safer and more resource efficient approach to diagnosis.

 

In The Lancet Global Health, Epicentre contributed to research validating a treatment decision algorithm for diagnosing tuberculosis in children living with HIV across four African countries. Combining clinical symptoms, rapid diagnostic testing, and medical imaging, the tool successfully identified most children with tuberculosis and supported rapid treatment initiation.

 

Finally, Epicentre and MSF co-authored research in the Journal of Medical Virologyevaluating dried blood spots for hepatitis E testing during an outbreak in South Sudan. The findings support their use for outbreak surveillance where conventional blood sampling and cold chain transport are challenging.

 

The Royal Society of Tropical Medicine and Hygiene (RSTMH) Annual Meeting takes place in London on 15–16 October, exploring Equitable Partnerships in Global Health. The two-day programme brings together perspectives from research, clinical practice, policy, funding, and programme delivery.Register and view the full programme.

 

Best regards,

 

Maya Fenyk, Lillian Matthes, and Holly Baker with MSF-authored article assistance from Alys Barton and Amelia Zhao.

 

All MSF-authored publications can be found on the MSF Science Portal, as well as recordings, abstracts and posters from the MSF Scientific Days 2026 conference.

Antimicrobial resistance 

The Lancet Microbe • Article: Investigating the role of a non-synonymous mutation at dhfr codon 50 in maintaining sulphadoxine–pyrimethamine resistance in Plasmodium falciparum: a modelling study

PLOS Medicine • Article: Predicting resistance to fluoroquinolones among patients with rifampicin-resistant tuberculosis: A cross-country validation study

Tropical Medicine & International Health • Article: Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

TRSTMH • Article: Suboptimal management of Staphylococcus aureus bacteremia: a retrospective case series from a Nigerian tertiary hospital

BMC Health Services Research • Article: Mapping system dynamics shaping neonatal infection prevention and antimicrobial stewardship in Botswana

 

Climate change and Planetary Health

The Lancet Planetary Health • Article: Premature mortality and economic losses attributable to landscape fire-related PM2·5 in ten countries and territories: a causal analysis

The Lancet Oncology • Article: Long-term exposure to wildfire-related PM2·5 and overall survival of older patients with lung cancer: a retrospective, registry-based cohort study

 

Global health

The Lancet Global Health • Article: Global inequalities in cardiometabolic care and achievable cardiovascular risk reduction by wealth, region, and sex: a pooled analysis of individual participant data from 76 countries

The Lancet Regional Health • Article: Iodine nutrition, thyroid function, and thyroid autoimmunity four decades after Universal Salt Iodisation in India: a cross-sectional study among schoolchildren (ICMR-SALT-T 1)

PLOS Neglected Tropical Diseases • Article: Fecal biomarkers to characterize intestinal inflammation among children with medically attended Diarrhea across six low-resource settings: Findings from the enterics for global health (EFGH) Shigella surveillance study

Health Policy and Planning • Article: When digital systems stop working: a qualitative study of misalignment between the implementation of a human resources information system and health zone realities in the Democratic Republic of the Congo

Global Public Health • Article: Barriers for uptake of COVID antivirals in multicultural communities – Exploring health service provider’s reflections on inequities

BMC Health Services Research • Article: Determinants of district health information system 2 data utilization in public health facilities in Harari Regional States and Dire Dawa City Administration, Eastern Ethiopia

BMC Health Services Research • Article: Availability, utilization, and contribution of interpersonal communication job aids for immunization among frontline health workers in Ethiopia: a qualitative study
 

HIV

The Lancet • Article: Switch to injectable cabotegravir–rilpivirine given every 8 weeks in adolescents living with HIV with virological suppression in sub-Saharan Africa (LATA): a randomised, open-label, multicentre, 96-week non-inferiority trial

The Lancet Regional Health • Article: Virological and metabolic outcomes after switching to dolutegravir or rilpivirine in virologically suppressed adults with HIV in Thailand: an open-label, randomised, controlled, non-inferiority trial

TRSTMH • Article: Prevalence of steatotic liver disease phenotypes and liver fibrosis in people with HIV in Egypt
 

Infectious diseases

The Lancet Regional Health • Article: Soil-transmitted helminthiasis prevalence and infection intensity among school-going children in Timor-Leste after the prolonged interruption of deworming: a cross-sectional survey (2025)

The Lancet Regional Health • Article: Epidemiology of Kyasanur forest disease in India, 2000–2025: a systematic review and meta-analysis

The Lancet Infectious Diseases • Article: The risk of mpox false positive results in high transmission settings: evidence from a multi-site observational study in DR Congo

The BMJ Global Health • Article: Mpox in Africa: one year continental response outcomes and way forward

JAMA • News: Mpox Virus Transitions Toward Endemicity

PLOS Neglected Tropical Diseases • Article: Burden of 46 key pathogens among children in G20 countries, 2023: A systematic analysis and regional comparison

PLOS Neglected Tropical Diseases • Article: Impact of two rounds of azithromycin mass drug administration on active trachoma and ocular Chlamydia trachomatis infection in Naoero

PLOS Neglected Tropical Diseases • Article: Development, field-testing and optimization of tools to quantify soil-transmitted helminths in fecal sludge from school pit latrines in Ethiopia

TRSTMH • Article: Detection of monkeypox virus in persons presenting skin lesions; benefits of One Health in passive surveillance
 

Malaria

Malaria Journal • Article: Association between number of previous malaria episodes and treatment failure among children and adults with laboratory-confirmed Plasmodium infection treated with pyronaridine-artesunate in Gabon: a retrospective cohort study

 

Maternal and child health

The Lancet Regional Health • Article: Time to diagnosis of acute kidney injury and its predictors among outborn neonates in India: a competing-risk analysis of tele-ICU network data (2022–2024)

The BMJ Global Health • Article: Trajectories of child undernutrition in Ethiopia: a multivariate GEE approach

The BMJ Global Health • Article: More than a lack of resources: a mixed-methods assessment of the barriers and facilitators to infection prevention practices in three low-resource maternity units in Malawi

PLOS Neglected Tropical Diseases • Article: Placentas from healthy women living in a cutaneous leishmaniasis endemic region in Mexico harbor Leishmania mexicana parasites: Potential implications for pregnancy and neonatal outcomes

Malaria Journal • Article: Umbrella review and meta-analysis on malaria infection and associated factors among pregnant women in Africa, 2026

Clinical Infectious Diseases • Article: Antenatal STI Screening for Birth Outcomes: An Open Question

BMC Health Services Research • Article: A qualitative study of the communication and information needs of parents of preterm Infants in a tertiary health facility in Northeast Nigeria

 

Mental health

The Lancet Regional Health • Article: Economic burden of suicide deaths in India (2023): a retrospective, cross-sectional study

BMC Health Services Research • Article: Primary health care providers’ readiness to implement the WHO mental health Gap Action Programme Intervention Guide (mhGAP-IG) for alcohol use disorder in rural Uganda: a qualitative study using CFIR
 

Neglected tropical diseases

PLOS Neglected Tropical Diseases • Article: Relapsing fever revisited: New insights into neglected borrelial infections

PLOS Neglected Tropical Diseases • Article: A systematic review of ultrasound to predict severe disease in patients with dengue and other viral infections associated with hemorrhagic fevers

PLOS Neglected Tropical Diseases • Article: Epidemiological transitions of Visceral Leishmaniasis in G20 countries: A 33-year retrospective joinpoint and demographic decomposition analysis with 20-year ARIMA projections

PLOS Neglected Tropical Diseases • Article: Unveiling the seasonal dynamics of leishmaniosis: High-resolution monthly potential risk mapping and future expansion of Leishmania infantum in Europe

PLOS Neglected Tropical Diseases • Article: Co-designing the ‘LEAD’ strategy: A theory-informed stakeholder-led behavioural intervention to improve mass drug administration compliance for lymphatic filariasis elimination in an urban block of Odisha, India

PLOS Neglected Tropical Diseases • Article: Molecular epidemiology of pathogenic Leptospira spp. in Thailand during 2024–2025, with detection of Leptospira weilii in human clinical specimens

PLOS Neglected Tropical Diseases • Article: Metagenomic insights into pathogen diversity and public health risk of Haemaphysalis longicornis in Gansu Province of China

PLOS Neglected Tropical Diseases • Article: Absence of human yaws and detection of Haemophilus ducreyi in skin ulcers of school children near wildlife protected areas in Tanzania

Tropical Medicine & International Health • Article: The Last Mile for Leprosy: From Multidrug Therapy to Sustainable Zero

TRSTMH • Article: Transactions of the Royal Society of Tropical Medicine and Hygiene: The study that proved the causative agent of Sri Lankan cutaneous leishmaniasis is Leishmania donovani
 

Non-communicable diseases

The Lancet Regional Health • Article: The burden of early-onset colorectal cancer in the WHO Eastern Mediterranean Region: an analysis of GLOBOCAN 2022 data

The Lancet Oncology • Article: Burden of cancer in Africa, 1990–2023: a systematic analysis from the Global Burden of Disease Study 2023

The BMJ Global Health • Comment: Disability inclusion as a missing pillar of Africa’s non-communicable disease response

Tropical Medicine & International Health • Article: Renal and Functional Vulnerability in Hansen Disease: A Framework for Chronic Infectious Disability in Endemic Settings

BMC Health Services Research • Article: Evaluating diabetes and diabetic retinopathy healthcare services in Jakarta, Indonesia: current challenges and opportunities for improvement

 

Research and reporting

Malaria Journal • Article: Risk mapping and determinants of the potential presence of Anopheles stephensi in Benin: a geostatistical and logistic regression approach

Malaria Journal • Article: Agent-based models of malaria control in the vaccine era: a systematic review of WHO GTS 2016–2030 target alignment

Malaria Journal • Article: Mapping malaria risk zones using GIS-based multi-criteria evaluation in Ilu Aba Bora Zone, Western Ethiopia

Malaria Journal • Article: Diagnostic accuracy of a malaria rapid diagnostic test compared with polymerase chain reaction in Lao People’s Democratic Republic: a secondary data analysis

Malaria Journal • Article: Deep learning convolutional neural networks for morphological identification of field-caught Anopheles stephensi in Ethiopia, using smartphone images of specimens

Malaria Journal • Article: Diagnostic accuracy of routine malaria tests and antimalarial prescription practices at health facilities in a endemic setting in Uganda

Clinical Infectious Diseases • Article: Evaluating metagenomic sequencing as a stool-based diagnostic in children with presumptive TB in Uganda

Global Public Health • Article: Trace of the tracer: Techno-solutionism, surveillance and the ambivalent experiences of digital health in Türkiye’s COVID-19 response
 

Sexual and reproductive health

Global Public Health • Article: Between justice and mediation: Women’s grassroots leadership in responding to sexual violence in Uganda

BMC Health Services Research • Article: Availability and readiness of primary healthcare facilities in the provision of adolescent sexual and reproductive health services in two regions of Burkina Faso: a cross-sectional study

BMC Health Services Research • Article: “Provided power is there, it will be a good initiative”: healthcare provider perspectives on diagnostic screening for curable STIs during pregnancy in Botswana
 

Tuberculosis

The Lancet Respiratory Medicine • Article: Duration of effectiveness of tuberculosis preventive treatment across various tuberculosis burden settings: a systematic review and individual-participant meta-analysis

The Lancet Global Health • Article: External validation of a treatment decision algorithm for tuberculosis in children living with HIV: a diagnostic cohort study

Tropical Medicine & International Health • Article: Routine TB Surveillance as a Diagnostic Tool: Subnational Care Cascade Gaps in East Nusa Tenggara, Indonesia

Clinical Infectious Diseases • Article: Non-invasive options for pediatric tuberculosis diagnosis: the search continues