A study to assess the safety and efficacy of six-month regimens containing promising new and existing TB drugs.
Médecins Sans Frontières/Doctors Without Borders' (MSF) has partnered with the Republican Specialized Scientific Research Medical Centre Of Tuberculosis And Pulmonology (TBI) in Uzbekistan for the project – with sites proposed in the country’s flagship TB programme in the autonomous region of Karakalpakstan, western Uzbekistan and in the capital, Tashkent.
MSF has worked in partnership with the Ministry of Health for nearly two decades and currently supports the delivery of the innovative 'Comprehensive TB project for all' in Karakalpakstan.
In 2014, the project enrolled over 2,000 patients for first-line TB treatment and 607 for DR-TB treatment. People are treated on an outpatient basis where possible, avoiding the additional stress of hospitalisation and enabling them to remain at home, close to their families and social support networks.
MSF is also in dialogue with the Ministry of Health of the Kingdom of Swaziland about the possibility of undertaking clinical research to find much improved treatments for people with DR-TB.
As with all research, the proposals must first go through a rigorous national and international approval process in order to ensure that the highest patient safety, scientific and ethical standards are met before going ahead.