22 Sep 16 07 Aug 20

Global Health Review - 07 August 2020

This week, MSF co-authors a study in Conflict and Health evaluating the morbidity and mortality of newborns admitted into the Neonatal Intensive Care Unit in Al-Gomhoury Hospital Hajjah, Yemen. There was a disproportionate burden of neonatal morbidity and mortality in this context, with the main morbidity being prematurity and its complications, compounded by significant geographical barriers that could be overcome by using a community-based model of care.

MSF authors a letter in IJTLD describing how MSF-supported TB services in Mumbai, India, have adapted during the COVID-19 pandemic, and sets out the challenges faced and proposed solutions. Another MSF-authored letter in Journal of Palliative Care discusses the results of a study evaluating the knowledge, attitudes and practices of palliative healthcare providers in Bihar, India, and draws attention to the lack of awareness around palliative care and limited service provision in Bihar.

Finally, MSF contributes to a study in Nature Communications evaluating the possible interference between an Ebola vaccine and post-exposure antibody treatment in non-human primates. There was evidence of improved survival in vaccinated animals that received the antibody treatment following exposure to the Ebola virus, compared to those receiving either vaccination or antibody therapy alone, highlighting the potential of a combined approach to therapy in humans. 

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BMJ Global Health • Article : Impact of a free care policy on the utilisation of health services during an Ebola outbreak in the Democratic Republic of Congo: an interrupted time-series analysis

Nature Communications • Article ***MSF AUTHOR***: Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment

PLOS NTDs • Article : A flexible format LAMP assay for rapid detection of Ebola virus

Global health

PLOS NTDs • Review : Health services uptake among nomadic pastoralist populations in Africa: A systematic review of the literature

Journal of Palliative Care • Letter ***MSF AUTHOR***: Knowledge, Attitudes, and Practices Regarding Palliative Care: A Mixed-Methods Study from Bihar, India


PLOS ONE • Article ***MSF AUTHOR***: Routine viral load monitoring and enhanced adherence counselling at a public ART centre in Mumbai, India

Tropical Medicine and International Health • Article : The potential for quality assurance systems to save costs and lives: the case of early infant diagnosis of HIV

The Lancet HIV • Article : Outcomes of donor-derived superinfection screening in HIV-positive to HIV-positive kidney and liver transplantation: a multicentre, prospective, observational study

Infectious diseases

NEJM • Article : Phase 1 Trial of a Therapeutic Anti–Yellow Fever Virus Human Antibody


Malaria Journal • Article : Endemic Burkitt lymphoma: a complication of asymptomatic malaria in sub-Saharan Africa based on published literature and primary data from Uganda, Tanzania, and Kenya

Malaria Journal • Review : Global prevalence and mortality of severe Plasmodium malariae infection: a systematic review and meta-analysis

Maternal and child health

Oxford Medical Case Reports • Case Study ***MSF AUTHOR***: Painless: a case of congenital insensitivity to pain in a 5-year-old male

BMJ Global Health • Editorial : WHO recommendations on antenatal nutrition: an update on multiple micronutrient supplements

BMJ Global Health • Analysis : Just-in-time postnatal education programees to improve newborn care practices: needs and opportunities in low-resource settings

BMJ Global Health • Analysis : Refocusing vitamin A supplementation programmes to reach the most vulnerable

NEJM • Article : Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants

NEJM • Article : Respiratory Syncytial Virus Vaccination during Pregnancy and Effects in Infants

Conflict and Health • Article ***MSF AUTHOR***: Morbidities & outcomes of a neonatal intensive care unit in a complex humanitarian conflict setting, Hajjah Yemen: 2017-2018

BMJ Opinion • Opinion : Covid-19 threatens to unravel years of progress on reproductive health and rights

The Lancet • Comment : Child malnutrition and COVID-19: the time to act is now

The Lancet • Comment : Impacts of COVID-19 on childhood malnutrition and nutrition-related mortality

The Lancet Global Health • Article : Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17

The Lancet Global Health • Article : Net benefit and cost-effectiveness of universal iron-containing multiple micronutrient powders for young children in 78 countries: a microsimulation study and comment The role of modelling to inform context-specific anaemia programming

The Lancet Child and Adolescent Health  • Article : Development of locally relevant clinical guidelines for procedure-related neonatal analgesic practice in Kenya: a systematic review and meta-analysis and comment Neonatal pain management in sub-Saharan Africa

Neglected tropical diseases

PLOS NTDs • Article : A new diagnostic strategy which uses a luminol-H2O2 system to detect helminth eggs in fecal sediments processed by the Helmintex method

PLOS NTDs • Article : The genus Madurella: Molecular identification and epidemiology in Sudan

PLOS NTDs • Article : Gene design, optimization of protein expression and preliminary evaluation of a new chimeric protein for the serological diagnosis of both human and canine visceral leishmaniasis

Tropical Medicine and International Health • Article : Spatial patterns and temporal tendency of mortality related to Chagas disease in an endemic area of northeastern Brazil

BugBitten • Viewpoint : Are kissing bugs moving to the city?

Non-communicable diseases

BMJ Global Health • Viewpoint : Time to apply a social determinants of health lens to addressing sickle cell disorders in sub-Saharan Africa


BMJ • Editorial : Cellular immune responses to covid-19

BMJ • Review : Drug treatments for covid-19: living systematic review and network meta-analysis

BMJ • Editorial : Covid-19 in Latin America

BMJ • Letter : Covid-19: UK Obstetric Surveillance System (UKOSS) study in context

BMJ • News : Covid-19: Deaths in Yemen are five times global average as healthcare collapses

BMJ Global Health • Viewpoint : Learning from Exemplars in Global Health: a road map for mitigating indirect effects of COVID-19 on maternal and child health

BMJ Global Health • Article : The remaining unknowns: a mixed methods study of the current and global health research priorities for COVID-19

JAMA • Viewpoint : COVID-19 and Dexamethasone

PLOS Medicine • Article : Estimation of SARS-CoV-2 mortality during the early stages of an epidemic: A modeling study in Hubei, China, and six regions in Europe

PLOS Medicine • Article : Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China

International Health • Article : COVID-19 and neglected tropical diseases in Africa: impacts, interactions, consequences

Conflict and Health • Viewpoint : COVID-19 control in low-income settings and displaced populations: what can realistically be done?

The Lancet • World Report : COVID-19 has “devastating” effect on women and girls

The Lancet Respiratory Medicine • Article : Observations of the global epidemiology of COVID-19 from the prepandemic period using web-based surveillance: a cross-sectional analysis

Mind and Society • Article ***MENTIONS MSF***: Some reflections about diverse responses to the COVID-19 pandemic

Research and reporting

The Lancet Respiratory Medicine • Article : Time-varying intensity of mechanical ventilation and mortality in patients with acute respiratory failure: a registry-based, prospective cohort study

Sexual and reproductive health

The Lancet Global Health • Editorial : Headway and hindrances for sexual and reproductive health and rights


The Union • Letter ***MSF AUTHOR***: Adapting TB services during the COVID-19 pandemic in Mumbai, India