Ebola is so infectious that patients need to be treated in isolation by staff wearing protective clothing.
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Since the Ebola outbreak in West Africa was officially declared on 22nd March in Guinea, it has claimed 5,420 lives in the region.
The outbreak is the largest ever, and is currently affecting four countries in West Africa: Guinea, Liberia, Sierra Leone and Mali. One person in Spain and three people in the USA have recovered; one person in the USA has died.
Outbreaks in Nigeria and Senegal have been declared over. A separate outbreak in Democratic Republic of Congo has also ended.
Following announcements made in the last weeks, deployment of international aid is slowly rolling out in the three main countries affected: Sierra Leone, Liberia and Guinea.
However, there is little indication that current efforts to increase capacity to isolate and take care of suspected and confirmed Ebola cases will address needs sufficiently.
Last week, MSF and three research institutions announced that clinical trials for three different treatments would be carried out at MSF sites in West Africa.
The United Nations Mission for Ebola Emergency Response (UNMEER) has been set up and will be based in Ghana to pursue five strategic priorities: stop the spread of the disease; treat the infected; ensure essential services; preserve stability; and prevent the spread of the disease to countries currently unaffected.
MSF teams in West Africa are still seeing critical gaps in all aspects of the response, including medical care, training of health staff, infection control, contact tracing, epidemiological surveillance, alert and referral systems, community education and mobilisation.
MSF has been responding to the outbreak since March, and currently has more than 3,436 staff working in Guinea, Liberia, Sierra Leone and Mali, treating an increasing number of patients.
Since the response began, 24 MSF staff members have fallen ill with Ebola, 11 of whom have recovered. The vast majority of these infections were found to have occurred in the community.
Since the beginning of our Ebola response, we have sent 1,201 tonnes of cargo to West Africa.
MSF case numbers since the outbreak began (as of 17th November)
Guinea: Admissions* - 2,386 | Confirmed - 1,254 | Recovered - 510
Sierra Leone: Admissions - 1,391 | Confirmed - 1,027 | Recovered - 481
Liberia: Admissions - 2,345 | Confirmed - 1,532 | Recovered - 608
Total: Admissions - 6,122 | Confirmed - 3,813 | Recovered - 1,599
* Admissions include all suspected, probable and confirmed cases.
Hover over the image below for an interactive guide to an MSF Ebola treatment centre
Hover over the image below for an interactive guide to the high risk zone inside an MSF Ebola treatment centre
Hover over the image below for an interactive guide to our Ebola protective kit
It is estimated there had been over 1,800 cases of Ebola, with nearly 1,300 deaths, before this latest outbreak in 2014.
The Ebola virus was first associated with an outbreak of 318 cases of a haemorrhagic disease in Zaire (now the Democratic Republic of Congo) in 1976. Of the 318 cases, 280 died — and died quickly.
That same year, 284 people in Sudan also became infected with the virus, killing 156.
There are five different strains of the Ebola virus: Bundibugyo, Ivory Coast, Reston, Sudan and Zaire, named after their places of origin.
Four of these five have caused disease in humans. While the Reston virus can infect humans, no illnesses or deaths have been reported.
Risk of Ebola spreading
The risk of Ebola spreading to the UK is minimal, but to minimise it even further we need more resources to bring the outbreak under control in West Africa.
Before this outbreak, MSF has treated hundreds of people affected by Ebola in Uganda, Republic of Congo, the Democratic Republic of Congo (DRC), Sudan, Gabon and Guinea. In 2007, MSF entirely contained an epidemic of Ebola in Uganda.
What causes Ebola?
Ebola can be caught from both humans and animals. It is transmitted through close contact with blood, secretions, or other bodily fluids.
Healthcare workers have frequently been infected while treating Ebola patients. This has occurred through close contact without the use of gloves, masks or protective goggles.
In areas of Africa, infection has been documented through the handling of infected chimpanzees, gorillas, fruit bats, monkeys, forest antelope and porcupines found dead or ill in the rainforest.
Burials where mourners have direct contact with the deceased can also transmit the virus, whereas transmission through infected semen can occur up to seven weeks after clinical recovery.
No specific treatment or vaccine is yet available for Ebola
Symptoms of Ebola
Early on, symptoms are non-specific, making it difficult to diagnose.
The disease is often characterised by the sudden onset of fever, feeling weak, muscle pain, headaches and a sore throat. This is followed by vomiting, diarrhoea, rash, impaired kidney and liver function and, in some cases, internal and external bleeding.
Symptoms can appear from two to 21 days after exposure. Some patients may go on to experience rashes, red eyes, hiccups, chest pains, difficulty breathing and swallowing.
Diagnosing Ebola is difficult because the early symptoms, such as red eyes and rashes, are common.
Ebola infections can only be diagnosed definitively in the laboratory by five different tests.
Such tests are an extreme biohazard risk and should be conducted under maximum biological containment conditions. A number of human-to-human transmissions have occurred due to a lack of protective clothing.
“Health workers are particularly susceptible to catching it so, along with treating patients, one of our main priorities is training health staff to reduce the risk of them catching the disease whilst caring for patients,” said Henry Gray, MSF’s emergency coordinator, during an outbreak of Ebola in Uganda in 2012.Henry is also working on the current outbreak.
“We have to put in place extremely rigorous safety procedures to ensure that no health workers are exposed to the virus – through contaminated material from patients or medical waste infected with Ebola.”
No specific treatment or vaccine is yet available for Ebola.
Standard treatment for Ebola is limited to supportive therapy. This consists of hydrating the patient, maintaining their oxygen status and blood pressure and treating them for any complicating infections.
Despite the difficulty of diagnosing Ebola in its early stages, those who display its symptoms should be isolated and public health professionals notified.
Supportive therapy can continue with proper protective clothing until samples from the patient are tested to confirm infection.
Once a patient recovers from Ebola, they are immune to the strain of the virus they contracted.
MSF contained an outbreak of Ebola in Uganda in 2012 by placing a control area around the treatment centre.
An Ebola outbreak is officially considered at an end once 42 days have elapsed without any new confirmed cases.
This New York Times video gives a shocking insight into the current situation in Monrovia, Liberia.
Update 13th November
In the absence of specific treatments for Ebola, MSF announced today that it will host clinical trials in three Ebola treatment centres in West Africa.
The separate trials, which are aimed at quickly finding an effective therapy that can be used against the disease which has so far taken around 5,000 lives in the current outbreak in the region, will be led by three different research partners.
Update 11th November
It is with great relief that we can today confirm that Dr Craid Spencer was declared free of Ebola and discharged from HHC Bellevue Hospital Centre in New York. Dr Spencer contracted the virus while on assignment in Guinea.
Update 10th November
While the number of new Ebola cases reported in Liberia has declined in recent weeks, the outbreak is far from over and new hotspots continue to emerge across the country, MSF said today, warning that the international aid response must rapidly adapt to this new phase of the epidemic, or risk undermining progress made against Ebola.
Update 5th November
Since September, over 50,000 Ebola home protection kits have been distributed and MSF aims to deliver a total of 70,000, covering a target population of 245,000, in the coming weeks. Here, we follow an MSF team in charge of distributing the kits for a day in Monrovia.
Update 30th October
Update 28th October
MSF stated today that forced quarantine of asymptomatic health workers returning from fighting the Ebola outbreak in West Africa is not grounded on scientific evidence and could undermine efforts to curb the epidemic at its source.
MSF international president Joanne Liu said: "We need to be guided by science and not political agendas."
Update 24th October
MSF confirmed today that one of its international staff members who recently returned from Guinea has tested positive for Ebola haemorrhagic fever.
The staff member, an American citizen, was placed in isolation on Thursday, 23rd October, at Bellevue Hospital in New York City, after developing a fever.
As per the specific guidelines that MSF provides its staff members on their return from Ebola assignments, the individual engaged in regular health monitoring and reported his first symptoms immediately to MSF.
Update 21st October
Today, we are celebrating the survival of our 1,000th Ebola patient in our centres in West Africa. Kollie James walked out of our treatment centre in Foya. In this update, his father Alexander - an MSF healthcare worker - tells Kollie's, and his family's, story.
Update 20th October
Update 17th October
MSF has taken the very difficult decision to temporarily suspend medical activities at Gondama Referral Centre, near Bo in Sierra Leone, because of the strain the current response to the Ebola outbreak in West Africa has put on the organisation’s capacity in the country. Overwhelmed teams means MSF cannot guarantee the extremely high quality of care needed to treat patients and protect MSF’s staff from infection.
Update 16th October
Salome Karwah is an Ebola survivor. After recovering from the virus, she came back to work at Médecins Sans Frontières/Doctors Without Borders (MSF) Elwa 3 treatment centre in Monrovia, Liberia, the very place she fought the disease.
Update 15th October
We take a look inside MSF's newest Ebola treatment centre in Bo, which just weeks after opening is already at full capacity. Three of the first patients to be discharged were siblings.
Dr Bertrand Draguez is MSF’s medical director currently working on the West Africa Ebola outbreak. In this update he explains why developing vaccines and treatments for Ebola is important, what is needed in order for them to make an impact in this outbreak, and why MSF is taking exceptional measures in facilitating clinical trials for potential treatments.
Update 10th October
Conakry, the first major city to be affected by the Ebola outbreak in West Africa, is currently seeing a massive spike in cases. In July, case numbers appeared to decrease in Guinea, suggesting the end of the outbreak might be near.
But Médecins Sans Frontières/Doctors Without Borders (MSF) is now caring for more than 120 patients, of whom 85 are confirmed to have the virus, in its two case management facilities in the country, Conakry and Guéckédou.
Update 9th October
On 29th September, a Ugandan man, aged around 30 and presenting symptoms of haemorrhagic fever, died in a hospital in the Ugandan capital, Kampala. On 4th October, the Centre for Disease Control and Prevention (CDC) announced that the man's blood tests had revealed contamination by Marburg fever.
Médecins Sans Frontières/Doctors Without Borders (MSF), which has been working in Uganda since 1986, is currently mobilising its teams in preparation for a response.
Update 6th October
MSF confirms that one of its international staff members in Sierra Leone has been diagnosed with Ebola haemorrhagic fever.
The staff member, a Norwegian national on assignment in the city of Bo, was placed in isolation on Sunday, 5th October, after developing a fever. Laboratory tests confirmed Ebola infection.
Following MSF medical evacuation procedures, the staff member will soon be transferred/ to a specialised treatment centre in Europe.
Update 3rd October
Teams from MSF have begun distributing more than 50,000 family protection and home disinfection kits in Monrovia as part of the organisation’s Ebola response.
The kits are designed to give people some protection should a family member become ill and also allow them to disinfect their homes, reducing the chance that others in the household could become contaminated.
“We know these kits are not the solution to the Ebola crisis in Monrovia”, said Anna Halford, coordinator for the distribution. “But the scale of the epidemic, and the inadequacy of the response so far means that we are forced to take unprecedented and imperfect measures.”
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